A retrospective study of a new n-butyl-2-cyanoacrylate glue treatment with application guide light (VenaBlock) for the treatment of venous insufficiency
Introduction: This study aims to present the early results of a retrospective study of the use of novel N-butyl-2 cyanoacrylate (VenaBlock) based non-tumescent endovenous ablation with the guide light for the treatment of patients with varicose veins.
Materials and methods: 538 patients with lower limb venous insufficiency treated with VenaBlock Venous Closure System between April 2016–July 2016. Study enrolled adults aged between 21-70 years with symptomatic moderate to severe varicosities (C2-C4b) and GSV reflux lasting longer than 0.5 second with GSV diameter≥ 5.5 mm and≤ 15 mm assessed in the standing position. Duplex ultrasound imaging and clinical followup were performed immediately after procedure. Clinical follow-up were performed at 3rd day, 1st month and 6th month Duplex ultrasound performed by an independent radiologist at 3rd day, 1st month and 6th month. Results: Mean treatment length was 25.69±4.88 cm and the average NBCA delivered was 0.87±0.15 ml. Mean procedure time was 11.75±4.97 minutes. Procedural success was% 100 and complete occlusion observed after treatment and at 3rd day follow-up. Ecchymosis was observed at 3rd day follow up in initial 5 patients (1.00%) at entry site. Phlebitis was encountered with 6 (1.20%) patients. No skin pigmentation, hematoma, paresthesia, deep vein thrombosis or pulmonary embolism was observed. Kaplan-Meier analysis yielded an occlusion rate of 99.6% at 6 months of follow-up. All patients had significant improvement in VCSS and AVVQ scores postoperatively (p< 0.0001). VCSS scores decreased from 5.43±0.87 to 1.03±0.96. AVVQ scores decreased …
